Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666922 | 0.95 | TP53 (0.58) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL4740482 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL9664195 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL4062526 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL4743986 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL9666989 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL4740473 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL9664702 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL4744095 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 | |
| SCHEMBL9664155 | 0.94 | TP53 (0.57) | TP53LTB4R2AGTR1NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |