Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 6/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716922 | 1.00 | PPARG (0.56) | PPARGCNR2GPR88BCHEACHE | |
| SCHEMBL9716990 | 1.00 | PPARG (0.56) | PPARGCNR2GPR88BCHEACHE | |
| SCHEMBL9716988 | 1.00 | PPARG (0.56) | PPARGCNR2GPR88BCHEACHE | |
| SCHEMBL9716865 | 0.89 | CNR2 (0.54) | PPARGCNR2GPR88BCHEHDAC8 | |
| SCHEMBL9716861 | 0.89 | CNR2 (0.54) | PPARGCNR2GPR88BCHEHDAC8 | |
| SCHEMBL9717048 | 0.84 | CNR2 (0.52) | CNR2GPR88HDAC8NOS2NOS3 | |
| SCHEMBL9716927 | 0.84 | CNR2 (0.52) | CNR2GPR88HDAC8NOS2NOS3 | |
| SCHEMBL9716930 | 0.84 | CNR2 (0.52) | CNR2GPR88HDAC8NOS2NOS3 | |
| SCHEMBL9717013 | 0.84 | CNR2 (0.52) | CNR2GPR88HDAC8NOS2NOS3 | |
| SCHEMBL9717052 | 0.84 | CNR2 (0.52) | CNR2GPR88HDAC8NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009561-A1 | NEW AMIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-06-11 | — | — | WO | disclosed |