SCHEMBL9716963

SCHEMBL9716963

CCCCOc1ccccc1C=CC(=O)NC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.49
NOS3 P29474 2/20 0.47
NOS1 P29475 2/20 0.47
NOS2 P35228 2/20 0.47
GALR1 P47211 1/20 0.46
PTGER1 P34995 1/20 0.44
PTGER4 P35408 1/20 0.44
PTGER3 P43115 1/20 0.44
PTGER2 P43116 1/20 0.44
HDAC8 Q9BY41 2/20 0.43
ALDH1A1 P00352 3/20 0.43
HTT P42858 2/20 0.43
NCOA1 Q15788 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
MAPT P10636 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GPR88 Q9GZN0 1/20 0.43
CCR3 P51677 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716965 1.00 CNR2 (0.49) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9716962 1.00 CNR2 (0.49) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9717048 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9717046 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9717013 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9717052 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9716927 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9716930 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9717009 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1
SCHEMBL9717010 0.96 CNR2 (0.52) CNR2NOS3NOS1NOS2GALR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992009561-A1 NEW AMIDE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-06-11 WO disclosed