Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523910 | 0.97 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL23888118 | 0.85 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL2222055 | 0.83 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL15258087 | 0.80 | — | — | |
| SCHEMBL14031553 | 0.77 | PTPN1 (0.30) | PTPN1 | |
| SCHEMBL20090022 | 0.75 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL31643928 | 0.73 | — | — | |
| SCHEMBL6544046 | 0.73 | PTPN1 (0.38) | PTPN1 | |
| SCHEMBL20088308 | 0.72 | POLB (0.33) | — | |
| SCHEMBL12634263 | 0.71 | PTPN1 (0.30) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153344-A | Vitamin E intermediates and a process for their manufacture and conversion into vitamin E | HOFFMAN-LA ROCHE INC. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0269009-B1 | METHOD FOR THE PRODUCTION OF CARBINOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-31 | — | — | EP | disclosed |
| US-5034546-A | Novel vitamin E intermediates and a process for their manufacture and conversion into vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4996375-A | Vitamin E intermediates and a process for their manufacture and conversion into Vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1991-02-26 | — | — | US | disclosed |
| US-4851585-A | Vitamin E intermediates | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0269009-A2 | Method for the production of carbinol derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-06-01 | — | — | EP | disclosed |