Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19592213 | 1.00 | NPSR1 (0.52) | NPSR1HCAR2ATMGLO1ALDH1A1 | |
| SCHEMBL2288560 | 0.88 | NPSR1 (0.65) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL4205886 | 0.88 | NPSR1 (0.65) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL2288565 | 0.88 | NPSR1 (0.65) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL28912588 | 0.86 | NPSR1 (0.63) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL28855755 | 0.86 | NPSR1 (0.63) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL30000293 | 0.86 | NPSR1 (0.63) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL9717298 | 0.85 | ATM (0.55) | NPSR1HCAR2ATMALDH1A1TSHR | |
| SCHEMBL8642959 | 0.85 | HCAR2 (0.50) | NPSR1HCAR2ATMALDH1A1CYP2D6 | |
| SCHEMBL8642958 | 0.81 | HCAR2 (0.46) | NPSR1HCAR2ATMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445219-A4 | SILSESQUIOXANE OLIGOMERS AND OPTICAL GLASS FIBER COATING COMPOSITIONS CONTAINING THE SAME | — | 1992-01-15 | — | — | EP | disclosed |
| WO-1991017198-A1 | LIQUID COMPOSITION COMPRISING SILICONE OLIGOMERS | STAMICARBON B.V. (NL) | 1991-11-14 | — | — | WO | disclosed |
| EP-0445219-A1 | SILSESQUIOXANE OLIGOMERS AND OPTICAL GLASS FIBER COATING COMPOSITIONS CONTAINING THE SAME | DESOTO INC. (US) | 1991-09-11 | — | — | EP | disclosed |
| WO-1990005752-A1 | SILSESQUIOXANE OLIGOMERS AND OPTICAL GLASS FIBER COATING COMPOSITIONS CONTAINING THE SAME | DESOTO, INC. (US) | 1990-05-31 | — | — | WO | disclosed |