Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440343 | 1.00 | HSD17B3 (0.56) | HSD17B3LMNAHSD17B10SLC6A2SLC6A3 | |
| SCHEMBL9440105 | 1.00 | HSD17B3 (0.56) | HSD17B3LMNAHSD17B10SLC6A2SLC6A3 | |
| SCHEMBL9717229 | 0.98 | HSD17B3 (0.54) | HSD17B3LMNAHSD17B10SLC6A2SLC6A3 | |
| SCHEMBL9324332 | 0.95 | HSD17B3 (0.51) | HSD17B3LMNAHSD17B10SLC6A2SLC6A3 | |
| SCHEMBL9405582 | 0.95 | HSD17B3 (0.51) | HSD17B3LMNAHSD17B10SLC6A2SLC6A3 | |
| SCHEMBL28728629 | 0.93 | HSD17B3 (0.53) | HSD17B3LMNAHSD17B10SLC6A2SLC6A3 | |
| SCHEMBL19277868 | 0.88 | CA1 (0.47) | HSD17B3CA1KDM4EMMP2MMP9 | |
| SCHEMBL9717236 | 0.87 | TP53 (0.53) | TSHRALDH1A1TP53MMP2MMP9 | |
| SCHEMBL9717304 | 0.87 | RARB (0.50) | HSD17B3LMNAHSD17B10ALDH1A1EGFR | |
| SCHEMBL17198848 | 0.86 | SLC6A2 (0.55) | HSD17B3LMNAHSD17B10SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137653-A | Alkanoyl ester compounds and their intermediates and method of producing the same | NIPPON MINING CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0311692-B1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |