SCHEMBL9717334

SCHEMBL9717334

C=CCOC(=O)OC(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
TSHR P16473 3/20 0.49
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 1/20 0.49
PKM P14618 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 2/20 0.46
KMT2A Q03164 3/20 0.44
MAPK1 P28482 2/20 0.44
HIF1A Q16665 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SNCA P37840 1/20 0.44
LMNA P02545 3/20 0.44
F2 P00734 1/20 0.44
RHOA P61586 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 2/20 0.41
AKT1 P31749 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28326808 0.88 CYP3A4 (0.62) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL21007 0.85 CYP3A4 (0.69) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL28343462 0.85 CYP3A4 (0.69) CYP3A4TSHRALDH1A1HSD17B10PKM
Benzene SCHEMBL28207781 0.85 CYP3A4 (0.69) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL11804204 0.84 CYP3A4 (0.62) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL11306827 0.84 CYP3A4 (0.67) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL2788103 0.84 CYP3A4 (0.67) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL1355708 0.84 CYP3A4 (0.67) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL7587574 0.84 CYP3A4 (0.67) CYP3A4TSHRALDH1A1HSD17B10PKM
SCHEMBL11786326 0.84 CYP3A4 (0.67) CYP3A4TSHRALDH1A1HSD17B10PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP claimed
CN-105969404-B Liquid crystal aligning agent, liquid crystal alignment film formed by liquid crystal aligning agent and liquid crystal display element 奇美实业股份有限公司 2018-03-23 CN disclosed
US-5137653-A Alkanoyl ester compounds and their intermediates and method of producing the same NIPPON MINING CO., LTD. (JP) 1992-08-11 US disclosed
EP-0311692-B1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1992-07-08 EP disclosed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP disclosed
US-4378366-A HYPOTENSIVE AND CARDIOTONIC AGENTS; ADRENERGIC STIMULANTS SCIENCE UNION ET CIE (FR) 1983-03-29 US disclosed