SCHEMBL971760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4701477	0.94	SMN1; SMN2 (0.42)	SMN1; SMN2NPC1RAB9AALDH1A1MAPK1
	SCHEMBL972810	0.90	ACKR3 (0.38)	ALDH1A1GRM5BTKHRH3SMPD3
	SCHEMBL973921	0.90	SMN1; SMN2 (0.38)	SMN1; SMN2NPC1RAB9AALDH1A1MAPK1
	SCHEMBL975080	0.89	SMPD3 (0.39)	SMN1; SMN2NPC1RAB9AFAAHBTK
	SCHEMBL972950	0.87	GRM5 (0.40)	GRM5HRH3CA12CA1CA2
	SCHEMBL974402	0.87	BTK (0.37)	NPC1RAB9AGRM5BTKCA12
	SCHEMBL973545	0.86	BTK (0.45)	GRM5BTKHRH3SMPD3ACKR3
	SCHEMBL973612	0.85	SMPD3 (0.41)	SMN1; SMN2NPC1RAB9AMAPK1GRM5
	SCHEMBL4704099	0.84	HRH3 (0.40)	SMN1; SMN2NPC1RAB9AALDH1A1GRM5
	SCHEMBL973224	0.83	GRM5 (0.40)	GRM5FAAHBTKHRH3SMPD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.