Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717823 | 1.00 | MAPT (0.53) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL6135463 | 0.94 | MAPT (0.59) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL834439 | 0.94 | MAPT (0.59) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL28666581 | 0.94 | MAPT (0.59) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL11490209 | 0.94 | MAPT (0.59) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL10888544 | 0.92 | MAPT (0.53) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL10886771 | 0.92 | MAPT (0.53) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL10886776 | 0.92 | MAPT (0.53) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL10888549 | 0.92 | MAPT (0.53) | MAPTUSP2SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL5716961 | 0.88 | SMN1; SMN2 (0.44) | MAPTUSP2SMN1; SMN2CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118837-A | Reaction of olefinic double bond in presence of other, less reactive olefinic double bonds; modified ruthenium catalyst with trivalent phosphorus or nitrogen or divalent sulfur compound | GIVAUDAN CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |