SCHEMBL9717994

SCHEMBL9717994

O=C1c2ccccc2C(=O)[N+]1(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CDC25B P30305 3/20 0.41
MAPT P10636 4/20 0.39
LMNA P02545 3/20 0.39
MAPK1 P28482 3/20 0.39
HTT P42858 3/20 0.39
MAOA P21397 2/20 0.39
APAF1 O14727 2/20 0.39
TDP2 O95551 2/20 0.39
POLB P06746 2/20 0.39
S100A4 P26447 2/20 0.39
RECQL P46063 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CES2 O00748 1/20 0.39
TERT O14746 1/20 0.39
NPC1 O15118 1/20 0.39
PLIN1 O60240 1/20 0.39
S1PR4 O95977 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043861 0.72 CDC25B (0.40) MEN1KMT2ACDC25BMAPTLMNA
SCHEMBL6694566 0.68 KMT2A (0.41) MEN1KMT2ACDC25BMAPTMAPK1
SCHEMBL10321305 0.67 CDC25B (0.45) MEN1KMT2ACDC25BMAPTLMNA
SCHEMBL29309539 0.65 KMT2A (0.43) MEN1KMT2ACDC25BMAPTLMNA
SCHEMBL11098184 0.63 CDC25B (0.41) MEN1KMT2ACDC25BMAPTLMNA
SCHEMBL19422810 0.62 KMT2A (0.39) MEN1KMT2ACDC25BMAPTLMNA
Anthraquinone SCHEMBL25230500 0.61 MEN1 (0.86) MEN1KMT2ACDC25BMAPTLMNA
Anthraquinone SCHEMBL183074 0.61 MEN1 (0.86) MEN1KMT2ACDC25BMAPTLMNA
SCHEMBL31290736 0.61 MEN1 (0.57) MEN1KMT2ACDC25BMAPTLMNA
Anthraquinone SCHEMBL14943 0.60 MEN1 (1.00) MEN1KMT2ACDC25BMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5106919-A Acrylic polymers of acids or esters imidized by an N-aryl amide, sulfonamide or urea; high glass transition temperatures MOUNTEDIPE S.R.L. (IT) 1992-04-21 US disclosed
EP-0382167-A1 Process for preparation of compatible mixtures of N-aryl polyglutarimides with styrene copolymers ENICHEM S.p.A. (IT) 1990-08-16 EP disclosed