Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689396 | 0.84 | TSHR (0.42) | BUB1TSHRRECQLTDP1MEN1 | |
| SCHEMBL28686165 | 0.83 | TSHR (0.39) | BUB1TSHRMEN1KMT2AFASN | |
| SCHEMBL10551544 | 0.80 | TSHR (0.37) | BUB1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8853968 | 0.79 | TSHR (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL8378717 | 0.78 | TSHR (0.68) | TSHRMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9718016 | 0.76 | TSHR (0.35) | TSHRRECQLTDP1MEN1KMT2A | |
| SCHEMBL10739830 | 0.70 | MEN1 (0.47) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL10682228 | 0.70 | MEN1 (0.39) | TSHRRECQLTDP1MAPTMEN1 | |
| SCHEMBL9349889 | 0.70 | MEN1 (0.49) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL10733254 | 0.70 | MEN1 (0.37) | TSHRMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270002-B1 | CYCLOHEXENONE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-04-15 | — | — | EP | disclosed |
| US-4820331-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-11 | — | — | US | disclosed |
| EP-0270002-A2 | Cyclohexenone derivatives | BASF Aktiengesellschaft (DE) | 1988-06-08 | — | — | EP | disclosed |