Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.45 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | ATIC | P31939 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790493 | 1.00 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL10125344 | 1.00 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL9010672 | 1.00 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL10041409 | 1.00 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL14107816 | 1.00 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL10712009 | 1.00 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL25314052 | 0.90 | CDC25A (0.53) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL25314057 | 0.90 | CDC25A (0.53) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL10041403 | 0.88 | NR1H4 (0.42) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL10041413 | 0.88 | NR1H4 (0.42) | CDC25ACDC25BNR1H4CYP24A1ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326875-B1 | DIDEHYDRO-VITAMIN D3 DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-25 | — | — | EP | disclosed |
| EP-0326875-A1 | Didehydro-vitamin D3 derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-08-09 | — | — | EP | disclosed |
| US-4804502-A | TREATMENT OF CALCIUM DEFICIENCY DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1989-02-14 | — | — | US | disclosed |
| US-4595776-A | Synthesis of 1α,25-dihydroxyergocalciferol | HOFFMANN-LA ROCHE INC. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4508651-A | Synthesis of 1α,25-dihydroxyergocalciferol | HOFFMANN-LA ROCHE INC. (US) | 1985-04-02 | — | — | US | disclosed |