⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433582 | 0.74 | — | — | |
| SCHEMBL27290172 | 0.74 | — | — | |
| SCHEMBL13971962 | 0.73 | — | — | |
| SCHEMBL19753035 | 0.73 | — | — | |
| SCHEMBL15354832 | 0.72 | — | — | |
| SCHEMBL22099351 | 0.72 | — | — | |
| SCHEMBL12643353 | 0.71 | — | — | |
| SCHEMBL1454989 | 0.71 | — | — | |
| SCHEMBL11124343 | 0.71 | — | — | |
| SCHEMBL20844929 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648243-B2 | Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2023-05-16 | — | — | US | disclosed |
| EP-2205281-B1 | PROTEIN-POLYMER CONJUGATES | PHARMAESSENTIA CORP (TW) | 2022-06-29 | — | — | EP | disclosed |
| WO-2022130270-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2022-06-23 | — | — | WO | disclosed |
| US-20210236415-A1 | SYNTHESIS AND APPLICATION OF MICROBUBBLE-FORMING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-08-05 | — | — | US | disclosed |
| EP-3372388-B1 | METHOD FOR FORMING THREE-DIMENSIONAL OBJECT | LG CHEMICAL LTD (KR) | 2020-04-22 | — | — | EP | disclosed |
| US-20180222886-A1 | VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS | Harbin Zhenbao Pharmaceutical Co., Ltd. (CN) | 2018-08-09 | — | — | US | disclosed |
| WO-2017133341-A1 | NOVEL IRREVERSIBLE BRUTON'S TYROSINE KINASE INHIBITOR | 中国科学院合肥物质科学研究院 | 2017-08-10 | — | — | WO | disclosed |
| WO-2017096056-A1 | OPTICAL SENSOR DEVICES, METHODS, AND SYSTEMS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-06-08 | — | — | WO | disclosed |
| US-20170107276-A9 | FC CONTAINING POLYPEPTIDES WITH ALTERED GLYCOSYLATION AND REDUCED EFFECTOR FUNCTION | GENZYME CORPORATION (US) | 2017-04-20 | — | — | US | disclosed |
| EP-2744521-B1 | DETECTION OF HYDROGEN PEROXIDE | PROMEGA CORP (US) | 2017-04-05 | — | — | EP | disclosed |
| US-6667330-B2 | Cytoprotective; neuroinflammation and neurodegenerative disorders; oxidative stress related conditions | GALILEO PHARMACEUTICALS, INC. | 2003-12-23 | — | — | US | disclosed |
| US-20030176361-A1 | Furanone derivatives | MONSANTO TECHNOLOGY LLC | 2003-09-18 | — | — | US | disclosed |
| WO-2003064403-A1 | FURANONE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| US-20030073712-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2003-04-17 | — | — | US | disclosed |
| WO-2003009807-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO LABORATORIES, INC. (US) | 2003-02-06 | — | — | WO | disclosed |
| US-20030013656-A1 | Pyruvate derivatives | ALLOY VENTURES, INC. | 2003-01-16 | — | — | US | disclosed |
| US-20030013846-A1 | Pyruvate derivatives | ALLOY VENTURES, INC. | 2003-01-16 | — | — | US | disclosed |
| US-20030013847-A1 | Cytoprotective agents | MONSANTO TECHNOLOGY LLC | 2003-01-16 | — | — | US | disclosed |
| US-20030013657-A1 | Pyruvate derivatives | MONSANTO TECHNOLOGY, LLC. | 2003-01-16 | — | — | US | disclosed |
| WO-2002090314-A1 | PYRUVATE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2002-11-14 | — | — | WO | disclosed |