Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216600 | 1.00 | SPHK1 (0.48) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL8406237 | 0.89 | FFAR1 (0.45) | FFAR1LMNAGMNNPOLBBLM | |
| SCHEMBL18620875 | 0.84 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL23879419 | 0.82 | SPHK1 (0.43) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL10821000 | 0.82 | SPHK1 (0.43) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL18191561 | 0.82 | SPHK1 (0.38) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL25735213 | 0.80 | SPHK1 (0.42) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL21086919 | 0.80 | SPHK1 (0.42) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL16290234 | 0.79 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL16290270 | 0.79 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267695-B1 | COMPOSITION COMPRISING A CARBOXYLIC ACID AND AN AMINE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-08 | — | — | EP | claimed |