Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637437 | 0.76 | TSHR (0.63) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8214255 | 0.75 | CA12 (0.56) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14850065 | 0.74 | TSHR (0.66) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30894823 | 0.74 | TSHR (0.66) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL761475 | 0.73 | TSHR (0.63) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7245111 | 0.73 | TSHR (0.63) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29645036 | 0.73 | TSHR (0.63) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1659363 | 0.72 | MAPT (0.71) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2612555 | 0.72 | MAPT (0.61) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL759752 | 0.71 | TSHR (0.61) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |