Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644211 | 0.84 | CES1 (0.49) | CES1LMNAALDH1A1CYP3A4TDP1 | |
| SCHEMBL14037792 | 0.76 | CES1 (0.59) | CES1LMNACES2ALDH1A1TDP1 | |
| SCHEMBL194188 | 0.74 | CES1 (0.51) | CES1LMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10957169 | 0.74 | CES1 (0.66) | CES1LMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2818433 | 0.73 | CES1 (0.50) | CES1LMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10779524 | 0.73 | CES1 (0.59) | CES1LMNACES2ALDH1A1TDP1 | |
| SCHEMBL11139906 | 0.73 | CES1 (0.50) | CES1LMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10226388 | 0.71 | CES1 (0.60) | CES1LMNACES2ALDH1A1CYP3A4 | |
| SCHEMBL14703576 | 0.71 | CES1 (0.46) | CES1LMNACES2ALDH1A1TDP1 | |
| SCHEMBL1645556 | 0.70 | CES1 (0.48) | CES1LMNACES2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |