Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.69 |
| ▸ | HTR1A | P08908 | 6/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9718820 | 0.99 | SETD7 (0.67) | SETD7HTR1ADRD2DRD3HTR7 | |
| SCHEMBL9718842 | 0.99 | SETD7 (0.67) | SETD7HTR1ADRD2DRD3HTR7 | |
| Hydrochloric Acid SCHEMBL9718711 | 0.97 | SETD7 (0.65) | SETD7HTR1ADRD2DRD3HTR7 | |
| SCHEMBL9718783 | 0.95 | SETD7 (0.64) | SETD7HTR1ADRD2DRD3HTR7 | |
| Hydrochloric Acid SCHEMBL9718733 | 0.94 | SETD7 (0.63) | SETD7HTR1ADRD2DRD3HTR7 | |
| SCHEMBL9718762 | 0.90 | SETD7 (0.61) | SETD7HTR1ADRD2DRD3HTR7 | |
| Hydrochloric Acid SCHEMBL7211736 | 0.87 | SETD7 (0.61) | SETD7HTR1ADRD2DRD3HTR7 | |
| SCHEMBL9718806 | 0.86 | SETD7 (0.52) | SETD7HTR1ADRD2DRD3CYP2D6 | |
| Hydrochloric Acid SCHEMBL9718721 | 0.85 | SETD7 (0.51) | SETD7HTR1ADRD2DRD3CYP2D6 | |
| Hydrochloric Acid SCHEMBL9718822 | 0.85 | SETD7 (0.65) | SETD7HTR1ADRD2DRD3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095022-A | Antiallergens | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0406739-A2 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |