Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.58 |
| ▸ | PTAFR | P25105 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718729 | 0.92 | SETD7 (0.55) | SETD7PTAFRMEN1MAPTKMT2A | |
| SCHEMBL9718809 | 0.91 | SETD7 (0.54) | SETD7PTAFRMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9718758 | 0.91 | SETD7 (0.54) | SETD7PTAFRMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9718827 | 0.89 | SETD7 (0.52) | SETD7PTAFRMEN1MAPTKMT2A | |
| SCHEMBL9718806 | 0.89 | SETD7 (0.52) | SETD7PTAFRMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9718721 | 0.88 | SETD7 (0.51) | SETD7PTAFRMEN1MAPTKMT2A | |
| SCHEMBL11600894 | 0.87 | PTAFR (0.63) | SETD7PTAFRMEN1MAPTKMT2A | |
| SCHEMBL9718791 | 0.86 | KCNH2 (0.56) | SETD7PTAFRMEN1MAPTKMT2A | |
| SCHEMBL3787169 | 0.85 | CYP2D6 (0.47) | SETD7PTAFRMEN1MAPTKMT2A | |
| SCHEMBL9718725 | 0.85 | PTAFR (0.60) | SETD7PTAFRMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095022-A | Antiallergens | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | claimed |
| EP-0406739-A2 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | claimed |
| US-5095022-A | Antiallergens | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |