Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718784 | 0.99 | KCNH2 (0.52) | KCNH2DRD3DRD2SETD7TP53 | |
| Hydrochloric Acid SCHEMBL9718782 | 0.99 | KCNH2 (0.52) | KCNH2DRD3DRD2SETD7TP53 | |
| Hydrochloric Acid SCHEMBL9718765 | 0.98 | KCNH2 (0.52) | KCNH2DRD3DRD2SETD7TP53 | |
| SCHEMBL9718719 | 0.97 | KCNH2 (0.54) | KCNH2DRD3DRD2SETD7TP53 | |
| Hydrochloric Acid SCHEMBL9718768 | 0.96 | KCNH2 (0.53) | KCNH2DRD3DRD2SETD7TP53 | |
| SCHEMBL9718791 | 0.92 | KCNH2 (0.56) | KCNH2DRD3DRD2SETD7MAPT | |
| SCHEMBL9718809 | 0.87 | SETD7 (0.54) | KCNH2DRD3DRD2SETD7MAPT | |
| SCHEMBL11601728 | 0.87 | KCNH2 (0.53) | KCNH2DRD3DRD2SETD7TP53 | |
| SCHEMBL9718806 | 0.86 | SETD7 (0.52) | DRD3DRD2SETD7MAPTPTAFR | |
| Hydrochloric Acid SCHEMBL9718827 | 0.86 | SETD7 (0.52) | KCNH2DRD3DRD2SETD7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095022-A | Antiallergens | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0406739-A2 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |