Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.60 |
| ▸ | HRH1 | P35367 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | HRH2 | P25021 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9718722 | 0.99 | SETD7 (0.59) | SETD7HRH1SLC6A2HRH2ALDH1A1 | |
| SCHEMBL9718794 | 0.93 | SETD7 (0.63) | SETD7HRH1SLC6A2HRH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9133954 | 0.92 | SETD7 (0.62) | SETD7HRH1SLC6A2HRH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9718731 | 0.91 | SETD7 (0.64) | SETD7HRH1SLC6A2HRH2ALDH1A1 | |
| SCHEMBL9718763 | 0.88 | SETD7 (0.63) | SETD7HRH1SLC6A2HRH2ALDH1A1 | |
| SCHEMBL9718777 | 0.87 | HRH1 (0.54) | SETD7HRH1SLC6A2HRH2HTR1A | |
| Hydrochloric Acid SCHEMBL9718778 | 0.86 | HRH1 (0.53) | SETD7HRH1SLC6A2HRH2HTR1A | |
| SCHEMBL11602777 | 0.84 | SETD7 (0.63) | SETD7HRH1SLC6A2HRH2ALDH1A1 | |
| SCHEMBL9718762 | 0.82 | SETD7 (0.61) | SETD7HRH1SLC6A2HRH2ALDH1A1 | |
| SCHEMBL8218752 | 0.81 | SETD7 (0.59) | SETD7HRH1SLC6A2HRH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095022-A | Antiallergens | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0406739-A2 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |