SCHEMBL9719170

SCHEMBL9719170

CC(F)(CC(F)(F)F)C(F)(F)C(F)(F)OC(=O)C=CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576164 0.84 HCAR2 (0.36) HCAR2
SCHEMBL9576361 0.81 HCAR2 (0.40) HCAR2
SCHEMBL9576304 0.81 HCAR2 (0.40) HCAR2
SCHEMBL29065867 0.80 TSHR (0.32)
SCHEMBL9576349 0.80 HCAR2 (0.42) HCAR2
SCHEMBL9576157 0.79 HCAR2 (0.37) HCAR2
SCHEMBL9719163 0.75 HCAR2 (0.43) HCAR2
SCHEMBL9576218 0.75 HCAR2 (0.44) HCAR2
SCHEMBL1321766 0.74 HCAR2 (0.42) HCAR2
SCHEMBL1320759 0.74 HCAR2 (0.42) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142009-A Crosslinked blend of fumaric acid diesters TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
US-4868260-A OXYGEN PERMEABILITY TOMEI SANGYO KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
EP-0219884-A2 Hard contact lens material Tomei Sangyo Kabushiki Kaisha (JP) 1987-04-29 EP disclosed