Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245743 | 0.87 | TAAR1 (0.46) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL5543511 | 0.85 | HDAC3 (0.49) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL386164 | 0.84 | TAAR1 (0.52) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL5547783 | 0.83 | HDAC3 (0.47) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL9127398 | 0.78 | IGF1R (0.53) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL896217 | 0.78 | TAAR1 (0.50) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL11400125 | 0.77 | IGF1R (0.52) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL6067810 | 0.77 | IGF1R (0.52) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL2094552 | 0.76 | KCNH2 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2657239 | 0.73 | TAAR1 (0.59) | IGF1RALOX15LMNATAAR1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492811-A1 | Antimicrobial composition and use | ZENECA LIMITED (GB) | 1992-07-01 | — | — | EP | disclosed |