SCHEMBL9719625

SCHEMBL9719625

OC(Cn1cncn1)(Cn1cncn1)c1ccccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.55
CYP19A1 P11511 5/20 0.55
CYP3A4 P08684 3/20 0.55
LMNA P02545 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP11B1 P15538 1/20 0.55
CYP11B2 P19099 1/20 0.55
CYP2C19 P33261 1/20 0.55
ADRA1A P35348 1/20 0.55
CYP51A1 Q16850 1/20 0.55
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.45
FDPS P14324 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.36
KCNN4 O15554 1/20 0.36
KCNA3 P22001 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10641438 0.91 CYP3A4 (0.47) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL8757392 0.89 HSP90AA1 (0.48) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL27308603 0.85 HSP90AA1 (0.52) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL27336818 0.83 CYP3A4 (0.50) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL27534083 0.83 HSP90AA1 (0.74) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL8057057 0.82 CYP3A4 (0.59) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
Hydrochloric Acid SCHEMBL11139113 0.82 HSP90AA1 (0.72) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL10856560 0.81 HSP90AA1 (0.41) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL9661070 0.81 KMT2A (0.67) HSP90AA1CYP19A1CYP3A4LMNACYP2C9
SCHEMBL5597155 0.81 CYP3A4 (0.51) HSP90AA1CYP19A1CYP3A4LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089640-A Fungicides, plant growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-4988382-A HERBICIDES, PLANT GROWTH REGULATORS, IMIDAZOLE DERIVATIVES, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
EP-0180136-B1 SUBSTITUTED AZOLYLMETHYL-CYCLOPROPYL CARBINOL DERIVATIVES BAYER AG (DE) 1991-01-02 EP disclosed
EP-0180838-B1 SUBSTITUTED AZOLYLCYCLOPROPYL-AZOLYLMETHYL-CARBINOL-DERIVATIVES BAYER AG (DE) 1990-05-16 EP disclosed
US-4921528-A PLANT GROWTH REGULATORS, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
US-4875928-A PLANT GROWTH REGULATORS, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-10-24 US disclosed
EP-0180838-A2 Substituted azolylcyclopropyl-azolylmethyl-carbinol-derivatives BAYER AG (DE) 1986-05-14 EP disclosed
EP-0180136-A2 Substituted azolylmethyl-cyclopropyl carbinol derivatives BAYER AG (DE) 1986-05-07 EP disclosed