⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299645 | 0.79 | — | — | |
| SCHEMBL11183858 | 0.69 | CYP2C19 (0.39) | — | |
| SCHEMBL11920711 | 0.66 | TP53 (0.37) | — | |
| SCHEMBL6815129 | 0.63 | — | — | |
| SCHEMBL1106749 | 0.62 | FFAR3 (0.36) | — | |
| SCHEMBL4480303 | 0.62 | — | — | |
| SCHEMBL4480305 | 0.62 | — | — | |
| SCHEMBL22323 | 0.60 | — | — | |
| SCHEMBL11385759 | 0.59 | FFAR3 (0.33) | — | |
| SCHEMBL7517446 | 0.59 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818552-B | Preparation method of 1-fluorocyclopropane carboxylic acid | 南京合巨药业有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-110818552-A | Preparation method of 1-fluorocyclopropane carboxylic acid | 南京合巨药业有限公司 | 2020-02-21 | — | — | CN | disclosed |
| US-5079374-A | Cyclopropyl-oxirane compounds as intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |
| US-4983208-A | Plant diseases, cereal crops | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |
| EP-0405267-A1 | Hydroxyethyl-cyclopropyl-azolyl derivatives | BAYER AG (DE) | 1991-01-02 | — | — | EP | disclosed |
| EP-0298332-B1 | HYDROXY-ALKYLAZOLYL DERIVATIVES | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |
| US-4925482-A | Fungicidal and plant growth-regulating hydroxyalkyl-azolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |