Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328862 | 0.89 | DPP4 (0.60) | DPP4KMT2APPARGPPARAPDCD1 | |
| SCHEMBL31261742 | 0.89 | DPP4 (0.60) | DPP4KMT2APPARGPPARAPDCD1 | |
| Biphenyl SCHEMBL15329765 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 | |
| SCHEMBL27304686 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 | |
| Methane SCHEMBL27607425 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 | |
| Ethane SCHEMBL3681665 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 | |
| Water SCHEMBL9719797 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 | |
| Ammonia Solution, Strong SCHEMBL27628949 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 | |
| SCHEMBL27779164 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 | |
| Hydrogen Sulfide SCHEMBL27801071 | 0.87 | DPP4 (0.58) | DPP4KMT2APPARGPPARAPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078906-A | Organic lithium-potassium complexes for metallization reactions, preparation of aspirin substitutes, fenoprofen | MINE SAFETY APPLIANCES COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0379987-A2 | Process for the preparation of alpha-arylalkanoic acids | Mine Safety Appliances Company (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4910337-A | Process for the preparation of α-arylalkanoic acids | MINE SAFETY APPLIANCES COMPANY (US) | 1990-03-20 | — | — | US | disclosed |