Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dexborneol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dexborneol SCHEMBL700565 | 1.00 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL9719849 | 1.00 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Borneol SCHEMBL9719854 | 1.00 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL28107044 | 0.92 | EPHX2 (0.42) | EPHX2ALDH1A1LMNA | |
| Borneol SCHEMBL28368233 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL23849409 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| (-)-Borneol SCHEMBL839194 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL20576252 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Borneol SCHEMBL20576251 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL3507513 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120037193-A | Improved preparation method of coronary heart disease storax pill | 同溢堂药业有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-120000772-A | Active quick-acting thrombolytic drug preparation device and preparation method thereof | 智昌药业(云南)有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-117503947-B | Medicine for repairing and protecting SH-SY5Y cell injury and preparation method thereof | 唐宁医药科技(济南)有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117503947-A | Medicine for repairing and protecting SH-SY5Y cell injury and preparation method thereof | 唐宁医药科技(济南)有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117164901-A | Starch-based dextrorotatory borneol microcapsule and preparation method and application thereof | 华南理工大学 | 2023-12-05 | — | — | CN | claimed |
| CN-114099629-B | Percutaneous administration preparation for treating breast nodules and preparation method thereof | 山东中医药大学 | 2023-09-22 | — | — | CN | claimed |
| CN-116585258-A | Thermosensitive in-situ gel for nasal administration of edaravone and borneol inclusion compound | 南京医科大学 | 2023-08-15 | — | — | CN | claimed |
| CN-116531351-A | Dextral borneol oral patch and preparation method and application thereof | 华南理工大学 | 2023-08-04 | — | — | CN | claimed |
| CN-116270437-A | Tannic acid ointment and preparation method thereof | 广西医大仙晟生物制药有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116270933-A | Zedoary ice antibacterial gel and preparation method thereof | 海南回元堂药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-107334868-A | A kind of Chinese medicine composition for treating xerophthalmia, preparation and preparation method thereof | 王艳萍 | 2017-11-10 | — | — | CN | claimed |
| CN-107184643-A | A kind of eyesight-improving health care function liquid containing snake gall and preparation method thereof | 深圳市欧斯特尔实业有限公司 | 2017-09-22 | — | — | CN | claimed |
| CN-107137603-A | A kind of traditional Chinese medicine composition for relieving asthenopia, preparation and preparation method thereof | 王艳萍 | 2017-09-08 | — | — | CN | claimed |
| CN-107041913-A | A kind of Chinese medicine composition, spray and the application phlebitis caused for venous transfusion | 山东大学齐鲁医院 | 2017-08-15 | — | — | CN | claimed |
| CN-104586972-B | Coptis extract solution for preventing and treating cow mastitis and preparation method thereof | 四川中农致远生物科技有限公司 | 2017-06-06 | — | — | CN | claimed |
| CN-106728236-A | It is a kind of to treat hemorrhoid and perianal eczema causes the compound Chinese medicinal preparation of itch | 合肥安德生制药有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106729087-A | A kind of Chinese medicine compound prescription external preparation for treating pruritus ani | 合肥安德生制药有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-105833105-A | Lung-clearing traditional Chinese medicine composition containing Cornu Saigae Tataricae and preparation method of lung-clearing traditional Chinese medicine composition containing Cornu Saigae Tataricae | 葵花药业集团（吉林）临江有限公司 | 2016-08-10 | — | — | CN | claimed |
| CN-103478179-A | Sterilizing agent used for plants and prepared by traditional Chinese medicinal materials | LIU JIYUAN | 2014-01-01 | — | — | CN | claimed |
| CN-102845481-A | Plant bactericide prepared from traditional Chinese medicinal materials | LIU JIYUAN | 2013-01-02 | — | — | CN | claimed |