Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719848 | 0.78 | MAPT (0.45) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9719840 | 0.77 | CYP1A2 (0.48) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL11177471 | 0.76 | GRM5 (0.50) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4208247 | 0.72 | NPC1 (0.47) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL11163593 | 0.70 | NPC1 (0.58) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL29405082 | 0.69 | NPC1 (0.59) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL432670 | 0.69 | NPC1 (0.59) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL11174365 | 0.69 | NPC1 (0.57) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8362996 | 0.67 | NPC1 (0.56) | DAOSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15355041 | 0.67 | CYP2C19 (0.52) | DAOSMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157039-A | Lipoxygenase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1992-10-20 | — | — | US | disclosed |
| US-5109009-A | QUINOLINE AND PYRIDINE COMPOUNDS AND INHIBITION OF 5-LIPOXYGENASES THEREWITH | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1992-04-28 | — | — | US | disclosed |
| US-4826987-A | Pyridyl and quinoline derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1989-05-02 | — | — | US | disclosed |