⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15124812 | 0.92 | — | — | |
| SCHEMBL27988568 | 0.90 | CYP1A2 (0.67) | — | |
| SCHEMBL30836939 | 0.90 | CYP1A2 (0.67) | — | |
| SCHEMBL4235132 | 0.90 | CYP1A2 (0.67) | — | |
| SCHEMBL15124720 | 0.90 | CYP1A2 (0.67) | — | |
| SCHEMBL4231630 | 0.90 | CYP1A2 (0.67) | — | |
| SCHEMBL233701 | 0.86 | — | — | |
| SCHEMBL27809378 | 0.80 | CYP1A2 (0.54) | — | |
| SCHEMBL1308391 | 0.78 | — | — | |
| SCHEMBL9086 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491037-A1 | COMPOUNDS | Respivert Limited (GB) | 2012-08-29 | — | — | EP | claimed |
| WO-2011048111-A1 | COMPOUNDS | RESPIVERT LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| US-20250223280-A1 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2025-07-10 | — | — | US | disclosed |
| US-12312340-B2 | Potent ASGPR-binding compounds for the degradation of immunoglobulins and other proteins | AVILAR THERAPEUTICS, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| CN-120035588-A | Aromatic acetylene derivative, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119306732-B | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-20250129118-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | H LEE MOFFITT CANCER CT & RES (US) | 2025-04-24 | — | — | US | disclosed |
| CN-113683622-B | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119306732-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119241554-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119219654-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-31 | — | — | CN | disclosed |
| EP-1157019-A1 | 4-ALKENYL (AND ALKYNYL) OXINDOLES AS INHIBITORS OF CYCLIN-DEPENDENT KINASES, IN PARTICULAR CDK2 | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-28 | — | — | EP | disclosed |
| US-6303793-B1 | INTERMEDIATES FOR CYCLIN-DEPENDENT KINASE INHIBITORS | HOFFMANN-LA ROCHE INC. | 2001-10-16 | — | — | US | disclosed |
| US-6252086-B1 | CYCLIN-DEPENDENT KINASES INHIBITORS; ANTICANCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-06-26 | — | — | US | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-6130239-A | INHIBIT CYCLIN-DEPENDENT KINASES | HOFFMANN-LA ROCHE INC. (US) | 2000-10-10 | — | — | US | disclosed |
| WO-2000035908-A1 | 4-ALKENYL (AND ALKYNYL) OXINDOLES AS INHIBITORS OF CYCLIN-DEPENDENT KINASES, IN PARTICULAR CDK2 | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0361772-A2 | Cyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1990-04-04 | — | — | EP | disclosed |