SCHEMBL9720012

SCHEMBL9720012

C=CCC1(O)C=CC(S(=O)(=O)C2C=CC(O)(CC=C)C=C2)C=C1.O=S(=O)(c1ccc(O)c(O)c1)c1ccc(O)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
SERPINE1 P05121 8/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
XDH P47989 1/20 0.33
APP P05067 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3179297 0.80
SCHEMBL9720013 0.71 POLB (0.42) POLBSERPINE1GAAMAPTXDH
SCHEMBL30110766 0.70 SERPINE1 (0.64) POLBSERPINE1GAAMAPTAPP
SCHEMBL1097599 0.70 SERPINE1 (0.64) POLBSERPINE1GAAMAPTAPP
SCHEMBL30320261 0.70 SERPINE1 (0.64) POLBSERPINE1GAAMAPTAPP
SCHEMBL7156223 0.65 POLB (0.49) POLBSERPINE1GAAMAPTXDH
SCHEMBL29420401 0.64 POLB (1.00) POLBGAAMAPTXDH
SCHEMBL28231 0.64 POLB (1.00) POLBGAAMAPTXDH
SCHEMBL3403169 0.64 POLB (1.00) POLBGAAMAPTXDH
SCHEMBL29375900 0.64 POLB (1.00) POLBGAAMAPTXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5081099-A A tetrahydronaphthalene sensitizer as antifogging agent; storage stability ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1992-01-14 US disclosed