Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439971 | 0.87 | PPARG (0.33) | — | |
| SCHEMBL9720200 | 0.87 | PPARG (0.33) | — | |
| SCHEMBL9720191 | 0.87 | PPARG (0.33) | — | |
| SCHEMBL9720180 | 0.86 | PPARA (0.32) | TLR2 | |
| SCHEMBL9720165 | 0.86 | PPARA (0.32) | TLR2 | |
| SCHEMBL9720208 | 0.84 | PPARA (0.30) | — | |
| SCHEMBL9720218 | 0.83 | — | — | |
| SCHEMBL9720195 | 0.82 | — | — | |
| SCHEMBL9716230 | 0.80 | PPARA (0.31) | — | |
| SCHEMBL10436740 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |