SCHEMBL9720320

SCHEMBL9720320

CC(O)CC(C)CC(C)CO

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 4/20 0.39
TRPA1 O75762 2/20 0.38
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98817 0.94
SCHEMBL27415706 0.87 TSHR (0.47) TDP1TSHRTRPA1
SCHEMBL2381959 0.87 TSHR (0.47) TDP1TSHRTRPA1
SCHEMBL5907063 0.84 TSHR (0.47) TDP1TSHRALDH1A1LMNA
SCHEMBL45749 0.84
SCHEMBL1328939 0.84
Acetic Acid SCHEMBL28340471 0.81 TDP1 (0.43) TDP1TSHRTRPA1ALDH1A1LMNA
Ammonia Solution, Strong SCHEMBL8993372 0.81 TSHR (0.44) TDP1TSHRALDH1A1LMNA
SCHEMBL15093596 0.80 TDP1 (0.47) TDP1TSHRALDH1A1LMNA
SCHEMBL18133250 0.80 TDP1 (0.47) TDP1TSHRTRPA1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110954-A Catalytic conversion to lactone E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-05 US disclosed
WO-1992000973-A1 DEHYDROGENATION OF DIOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-23 WO disclosed