Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 11/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720481 | 0.92 | TOP2A (0.56) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL7866482 | 0.91 | TOP2A (0.67) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9720548 | 0.91 | TOP2A (0.55) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9853310 | 0.91 | TOP2A (0.47) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9720463 | 0.90 | TOP2A (0.54) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9720480 | 0.90 | TOP2A (0.54) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9720466 | 0.89 | TOP2A (0.45) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9720493 | 0.89 | TOP2A (0.53) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9720598 | 0.89 | TOP2A (0.45) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL9720542 | 0.84 | TOP2A (0.55) | TOP2ATOP2BKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417669-A2 | Pyridinyl-quinolone compounds, their preparation and use | STERLING WINTHROP INC. (US) | 1991-03-20 | — | — | EP | claimed |
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5075319-A | Bactericides | STERLING DRUG INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0417669-A2 | Pyridinyl-quinolone compounds, their preparation and use | STERLING WINTHROP INC. (US) | 1991-03-20 | — | — | EP | disclosed |