Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660653 | 0.85 | PIK3CD (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL14959575 | 0.84 | SMN1; SMN2 (0.37) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL23660724 | 0.81 | TOP2A (0.36) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL9720746 | 0.73 | PTGS1 (0.56) | TOP2ATOP2BTDP1PIK3CD | |
| SCHEMBL9720744 | 0.73 | PTGS1 (0.56) | TOP2ATOP2BTDP1PIK3CD | |
| SCHEMBL9720830 | 0.73 | PTGS1 (0.56) | TOP2ATOP2BTDP1PIK3CD | |
| SCHEMBL9034496 | 0.72 | TOP2A (0.45) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL84388 | 0.71 | GSK3A (0.35) | GSK3AGSK3B | |
| Icrf-193 SCHEMBL729019 | 0.68 | TOP2A (1.00) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| Icrf-193 SCHEMBL14006976 | 0.68 | TOP2A (1.00) | TOP2ATOP2BALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000740-A2 | BIS-DIOXOPIPERAZINES AND THEIR USE AS PROTECTION AGENTS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-01-23 | — | — | WO | disclosed |