SCHEMBL972175

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL939867	0.93	PIK3CA (0.43)	PIK3CDPIK3CBMTORMAPK14TBK1
	SCHEMBL939309	0.87	AURKB (0.38)	FGFR1KDRTBK1FLT3
	SCHEMBL941158	0.86	RAF1 (0.39)	MAPK14FGFR1KDRTBK1FLT3
	SCHEMBL940283	0.86	FGFR1 (0.36)	PIK3CDPIK3CBMTORFGFR1TBK1
	SCHEMBL940272	0.86	MEN1 (0.43)	MAPK14FGFR1TBK1FLT3CCNT1
	SCHEMBL940095	0.86	AURKB (0.40)	MAPK14FGFR1KDRTBK1ALDH1A1
	SCHEMBL939356	0.86	POLB (0.43)	FGFR1KDRTBK1PTGESALDH1A1
	SCHEMBL938958	0.86	RAF1 (0.39)	PIK3CDPIK3CBMTORMAPK14FGFR1
	SCHEMBL939068	0.86	FGFR1 (0.40)	FGFR1KDRTBK1ALDH1A1
	SCHEMBL940043	0.86	PIK3CA (0.42)	PIK3CDPIK3CBMTORFGFR1TBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.