Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130030 | 0.83 | NCEH1 (0.46) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9858100 | 0.83 | KDM4E (0.47) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10593104 | 0.77 | BCHE (0.39) | TLR8 | |
| SCHEMBL10348232 | 0.76 | PTPN1 (0.49) | NCEH1 | |
| SCHEMBL1252091 | 0.74 | NCEH1 (0.47) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6919402 | 0.74 | NCEH1 (0.47) | KDM4EMEN1KMT2ASMN1; SMN2TLR8 | |
| SCHEMBL234512 | 0.72 | TYR (0.47) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2126531 | 0.72 | NCEH1 (0.49) | KDM4ETLR8NCEH1 | |
| SCHEMBL10800999 | 0.72 | NCEH1 (0.46) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL284699 | 0.72 | TYR (0.47) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310122-B1 | ANTIFUNGAL COMPOSITION | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-07-24 | — | — | EP | claimed |
| US-5120735-A | Synergistic mixture of miconazole, ketoconazole or fluconazole and N-4-tertbutylbenzyl-N-methyl-1-naphthalenemethylamine | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0310122-B1 | ANTIFUNGAL COMPOSITION | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |