Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479589 | 0.81 | CHRM2 (0.46) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL4396518 | 0.80 | PIK3CD (0.48) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL261644 | 0.77 | PIK3CD (0.58) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL28383074 | 0.77 | PIK3CD (0.46) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL17599243 | 0.75 | SMN1; SMN2 (0.41) | CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL21052112 | 0.75 | CHRM2 (0.47) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL5008301 | 0.74 | KMT2A (0.42) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL5424673 | 0.73 | PIK3CD (0.54) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL4394145 | 0.73 | KMT2A (0.47) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL18952994 | 0.72 | CHRM2 (0.34) | CHRM2CHRM5CHRM1CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162530-A | Hydrophilic modifier monomers | CIBA-GEIGY CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| US-5053515-A | Glutarimido and succinimido derivatives | CIBA-GEIGY CORPORATION (US) | 1991-10-01 | — | — | US | disclosed |
| US-4921956-A | Hydrophilic modifier monomers | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0331633-A2 | Hydrophilic modifier monomers | CIBA-GEIGY AG (CH) | 1989-09-06 | — | — | EP | disclosed |
| US-4859780-A | Hydrophilic modifier monomers | CIBA-GEIGY CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |