Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30284835 | 0.98 | GLA (0.53) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723777 | 0.95 | GLA (0.53) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723716 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723825 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723871 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9614326 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723826 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723839 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723776 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL9723852 | 0.93 | GLA (0.51) | GLARAB9AL3MBTL1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368933-B1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0368933-A1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4920101-A | FOR ENHANCING PENETRATION OF PHYSIOLOGICALLY ACTIVE AGENTS THROUGH SKIN OR OTHER MEMBRANES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4879275-A | Penetration enhancers for transdermal delivery of systemic agent | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-11-07 | — | — | US | disclosed |