Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029772 | 0.77 | CYP3A4 (0.78) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL12248741 | 0.77 | CYP3A4 (0.60) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL4743848 | 0.77 | CYP3A4 (0.66) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL13235630 | 0.76 | CYP3A4 (0.46) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL3620853 | 0.76 | NR1H4 (0.56) | CYP3A4MAPK1SMN1; SMN2KMT2APKM | |
| SCHEMBL23327352 | 0.75 | CYP3A4 (0.53) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL5209995 | 0.75 | CYP3A4 (0.53) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL23327273 | 0.75 | CYP3A4 (0.53) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL116728 | 0.75 | CYP3A4 (0.53) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A | |
| SCHEMBL23327143 | 0.75 | MAPK1 (0.53) | CYP3A4MAPK1SMN1; SMN2USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4342541-A | — | — | None | — | — | JP | disclosed |
| JP-H04342541-A | 2,6-ALKOXYPHENYL ALKYLKETONE AND HERBICIDAL DERIVATIVES | RHONE POULENC AGROCHIM | 1992-11-30 | — | — | JP | disclosed |