Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724797 | 0.91 | ELANE (0.57) | ELANEESR1HIF1AFFAR1MAPT | |
| SCHEMBL10422483 | 0.91 | ELANE (0.57) | ELANEESR1HIF1AFFAR1HSD17B10 | |
| SCHEMBL10421858 | 0.89 | ELANE (0.58) | ELANEESR1HIF1AFFAR1HSD17B10 | |
| SCHEMBL10358648 | 0.88 | ELANE (0.57) | ELANEESR1HIF1AFFAR1HSD17B10 | |
| SCHEMBL6937874 | 0.88 | ELANE (0.57) | ELANEESR1HIF1AFFAR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9724794 | 0.87 | HSD17B10 (0.54) | ELANEESR1HIF1AHSD17B10MAPT | |
| SCHEMBL10423518 | 0.86 | ELANE (0.56) | ELANEESR1HIF1AFFAR1HSD17B10 | |
| SCHEMBL10421845 | 0.84 | ELANE (0.53) | ELANEESR1HIF1AHSD17B10MAPT | |
| SCHEMBL27581241 | 0.83 | ELANE (0.59) | ELANEESR1HIF1AFFAR1MAPT | |
| SCHEMBL10423597 | 0.82 | ELANE (0.52) | ELANEESR1HIF1AHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100579-A | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0191600-B1 | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4911861-A | Mixture of at least two components | AJINOMOTO CO., INC. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4728458-A | FERROELECTRIC | AJINOMOTO CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0191600-A2 | Polyphenyl-based ester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1986-08-20 | — | — | EP | disclosed |