SCHEMBL9726219

SCHEMBL9726219

C[Al](C)C.[Li]c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.37
ACHE P22303 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
TDP1 Q9NUW8 3/20 0.33
ALDH1A1 P00352 2/20 0.33
CA4 P22748 2/20 0.32
TP53 P04637 1/20 0.32
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
CA12 O43570 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1136809 0.86
SCHEMBL28069 0.86
Methane SCHEMBL28886214 0.82
Ammonia Solution, Strong SCHEMBL8054312 0.82
Hydrochloric Acid SCHEMBL1949827 0.82
SCHEMBL9161603 0.82
SCHEMBL3808897 0.82
SCHEMBL1820268 0.82
Fluoride SCHEMBL29013919 0.82
Trimethylammonium SCHEMBL6912448 0.80 TSHR (0.39) TSHRACHELMNAALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166349-A CHIRAL ORGANOIRON COMPLEXES AND USE FOR ASSYMETRIC REDUCTION THE BRITISH PETROLEUM COMPANY, P.L.C. (GB) 1992-11-24 US disclosed
EP-0426474-A1 Chiral organometallic complexes and uses thereof The British Petroleum Company p.l.c. (GB) 1991-05-08 EP disclosed