SCHEMBL972622

SCHEMBL972622

CCCCCNC(=O)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.58
DPP7 Q9UHL4 2/20 0.55
CASP2 P42575 1/20 0.52
PLA2G2A P14555 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
NAAA Q02083 1/20 0.48
GNAI3 P08754 1/20 0.47
GNAO1 P09471 1/20 0.47
GNAI1 P63096 1/20 0.47
PLA2G4A P47712 1/20 0.47
SPHK1 Q9NYA1 3/20 0.46
RRM1 P23921 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9111268 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
SCHEMBL4066317 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
SCHEMBL5960404 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
SCHEMBL8962168 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
SCHEMBL8962332 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
SCHEMBL28983321 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
SCHEMBL7748456 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
SCHEMBL8962477 0.98 EPHX1 (0.61) EPHX1DPP7CASP2PLA2G2AZDHHC20
Ethane SCHEMBL28842141 0.96 EPHX1 (0.59) EPHX1DPP7CASP2PLA2G2AZDHHC20
Benzene SCHEMBL29129937 0.94 EPHX1 (0.52) EPHX1DPP7CASP2PLA2G2ANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4293331-A Novel acyloxamides and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US claimed
EP-0002455-B1 ACYLOXYAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR REGULATING THE GROWTH OF PLANTS BAYER AG (DE) 1980-11-26 EP claimed
EP-0002455-A1 Acyloxyamides, process for their preparation and their use for regulating the growth of plants BAYER AG (DE) 1979-06-27 EP claimed
JP-54084520-A None JP disclosed
CN-113271777-B Compositions comprising clopyralid and other herbicides and methods thereof 美国陶氏益农公司 2023-05-23 CN disclosed
US-20130224227-A1 NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS BYONDIS B.V. (NL) 2013-08-29 US disclosed
US-8067420-B2 Substituted pyrazinone melanin concentrating hormone receptor-1 antagonists and methods BRISTOL-MYERS SQUIBB COMPANY (US) 2011-11-29 US disclosed
US-8012984-B2 Substituted pyrazinone melanin concentrating hormone receptor-1 antagonists and methods BRISTOL-MYERS SQUIBB COMPANY (US) 2011-09-06 US disclosed
US-20110144060-A1 SUBSTITUTED PYRAZINONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS AND METHODS BRISTOL-MYERS SQUIBB COMPANY 2011-06-16 US disclosed
US-20110003759-A1 NON-BASIC MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS AND METHODS BRISTOL-MYERS SQUIBB COMPANY 2011-01-06 US disclosed
EP-2173725-A2 NON-BASIC MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS AND METHODS Bristol-Myers Squibb Company (US) 2010-04-14 EP disclosed
WO-1991013113-A1 OXYGEN BARRIER EXXON CHEMICAL PATENTS INC. (US) 1991-09-05 WO disclosed
US-4293331-A Novel acyloxamides and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
US-4293331-A Novel acyloxamides and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
US-4293331-A Novel acyloxamides and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
EP-0002455-B1 ACYLOXYAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR REGULATING THE GROWTH OF PLANTS BAYER AG (DE) 1980-11-26 EP disclosed
US-4217348-A Cephalosporins having an oxazolidonyloxamido substituted acyl sidechain E. R. SQUIBB & SONS, INC. (US) 1980-08-12 US disclosed
JP-S5484520-A NOVEL ACYL OXAMIDE* ITS MANUFACTURE AND USE AS PLANT GROWTH REGULATING AGENT BAYER AG 1979-07-05 JP disclosed
EP-0002455-A1 Acyloxyamides, process for their preparation and their use for regulating the growth of plants BAYER AG (DE) 1979-06-27 EP disclosed
EP-0002455-A1 Acyloxyamides, process for their preparation and their use for regulating the growth of plants BAYER AG (DE) 1979-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144060-A1 SUBSTITUTED PYRAZINONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS AND METHODS MCHR1, MC1R, MCHR2 EPHX1 1391/4885DPP7 728/4885CASP2 4501/4885
US-20110003759-A1 NON-BASIC MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS AND METHODS MCHR1, MCHR2, MC1R EPHX1 1017/4885DPP7 1542/4885CASP2 4667/4885
US-20130224227-A1 NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS PCNA, DCLRE1A, CDC5L EPHX1 2864/4885DPP7 2846/4885CASP2 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.