Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.79 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | LAP3 | P28838 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444558 | 0.95 | TSHR (0.75) | TSHRSRCANPEPLAP3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28976264 | 0.93 | TSHR (0.72) | TSHRSRCANPEPLAP3ALDH1A1 | |
| SCHEMBL51316 | 0.89 | TSHR (1.00) | TSHRSRCALDH1A1CETPAKR1C3 | |
| SCHEMBL27908642 | 0.89 | TSHR (1.00) | TSHRSRCALDH1A1CETPAKR1C3 | |
| SCHEMBL9446520 | 0.87 | TSHR (0.96) | TSHRSRCALDH1A1CETPAKR1C3 | |
| SCHEMBL11756554 | 0.87 | TSHR (0.96) | TSHRSRCALDH1A1CETPAKR1C3 | |
| Ammonia Solution, Strong SCHEMBL7268743 | 0.87 | TSHR (0.96) | TSHRSRCALDH1A1CETPAKR1C3 | |
| SCHEMBL4219700 | 0.87 | TSHR (0.96) | TSHRSRCALDH1A1CETPAKR1C3 | |
| SCHEMBL28032525 | 0.87 | TSHR (0.96) | TSHRSRCALDH1A1CETPAKR1C3 | |
| Hydrochloric Acid SCHEMBL10722992 | 0.87 | TSHR (0.96) | TSHRSRCALDH1A1CETPAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108997-A | Microbiocides | FUJISAWA PHARMACEUTICALS CO., LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| US-4927818-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |