Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 4/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | PDE6A | P16499 | 1/20 | 0.39 |
| ▸ | PDE6G | P18545 | 1/20 | 0.39 |
| ▸ | PDE6B | P35913 | 1/20 | 0.39 |
| ▸ | PDE6C | P51160 | 1/20 | 0.39 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726479 | 0.83 | BRD4 (0.50) | LMNAHPGDBRD4BRD9KAT2B | |
| SCHEMBL9726805 | 0.77 | BRD4 (0.53) | LMNAHPGDBRD4BRD9KAT2B | |
| SCHEMBL9726461 | 0.74 | BRD4 (0.49) | LMNAHPGDBRD4BRD9KAT2B | |
| SCHEMBL9828337 | 0.73 | BRD4 (0.46) | LMNAHPGDBRD4BRD9KAT2B | |
| SCHEMBL9726412 | 0.73 | BRD4 (0.53) | LMNABRD4BRD9KAT2BBPTF | |
| Hydrochloric Acid SCHEMBL9726406 | 0.73 | BRD4 (0.52) | LMNABRD4BRD9KAT2BBPTF | |
| SCHEMBL9726598 | 0.71 | BPTF (0.52) | LMNAHPGDBRD4BRD9KAT2B | |
| SCHEMBL15596726 | 0.71 | SMN1; SMN2 (0.42) | LMNAHPGDMEN1KMT2AITGB1 | |
| SCHEMBL9726537 | 0.71 | BRD4 (0.45) | LMNAHPGDBRD4BRD9KAT2B | |
| SCHEMBL9726415 | 0.70 | BRD4 (0.49) | LMNAHPGDBRD4BRD9KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |