Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.45 |
| ▸ | PDE9A | O76083 | 3/20 | 0.45 |
| ▸ | BPTF | Q12830 | 2/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726500 | 0.92 | BRD4 (0.46) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726408 | 0.92 | BRD4 (0.42) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726526 | 0.90 | BRD4 (0.44) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726512 | 0.88 | BRD4 (0.47) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726528 | 0.84 | BRD4 (0.52) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726508 | 0.82 | BRD4 (0.52) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726428 | 0.78 | BRD4 (0.56) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL10601213 | 0.77 | BRD4 (0.73) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726410 | 0.75 | BRD4 (0.70) | BRD4BRD9PDE9ABPTFKAT2B | |
| SCHEMBL9726565 | 0.74 | BPTF (0.45) | BRD4BRD9PDE9ABPTFKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |