Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726826 | 1.00 | HMGCR (0.54) | HMGCR | |
| SCHEMBL9727002 | 0.90 | HMGCR (0.56) | HMGCR | |
| SCHEMBL10611915 | 0.89 | HMGCR (0.57) | HMGCR | |
| SCHEMBL9726560 | 0.89 | HMGCR (0.44) | HMGCR | |
| SCHEMBL9726567 | 0.89 | HMGCR (0.44) | HMGCR | |
| SCHEMBL9726607 | 0.86 | HMGCR (0.62) | HMGCR | |
| SCHEMBL9726604 | 0.86 | HMGCR (0.62) | HMGCR | |
| SCHEMBL9726678 | 0.84 | HMGCR (0.38) | HMGCR | |
| SCHEMBL9726464 | 0.83 | HMGCR (0.77) | HMGCR | |
| SCHEMBL9726467 | 0.83 | HMGCR (0.77) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110940-A | Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase | BRISTOL-MYERS COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |