Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133313 | 0.90 | CYP2C19 (0.45) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL30438257 | 0.83 | MAPT (0.49) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6009928 | 0.83 | MAPT (0.49) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL9132456 | 0.79 | MAPT (0.47) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL9130975 | 0.78 | CYP2C19 (0.46) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL9132031 | 0.78 | MAPT (0.44) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL9134935 | 0.77 | MAPT (0.43) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL9131645 | 0.77 | MAPT (0.43) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL9134909 | 0.77 | MAPT (0.43) | CYP2C19KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL9132205 | 0.77 | PDE4D (0.43) | CYP2C19KMT2AMAPTHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126352-A | Antiallergy, antiinflammatory, antiulcer, hypotensive, antibody inhibitors | SCHERING CORPORATION (US) | 1992-06-30 | — | — | US | claimed |