Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17969114 | 0.87 | ERBB2 (0.37) | ERBB2DYRK1ACHEK1ABL1PDGFRB | |
| SCHEMBL17969113 | 0.87 | ERBB2 (0.37) | ERBB2DYRK1ACHEK1ABL1PDGFRB | |
| SCHEMBL16399388 | 0.85 | KDM4E (0.39) | ERBB2CHEK1GRM5ALDH1A1HPGD | |
| SCHEMBL16399387 | 0.85 | KDM4E (0.39) | ERBB2CHEK1GRM5ALDH1A1HPGD | |
| SCHEMBL25367734 | 0.82 | HRH3 (0.37) | ERBB2DYRK1ACHEK1ABL1PDGFRB | |
| SCHEMBL29145618 | 0.81 | ERBB2 (0.49) | ERBB2MAPK14ALDH1A1HPGDKMT2A | |
| SCHEMBL16397641 | 0.78 | NISCH (0.37) | ERBB2DYRK1ACHEK1ABL1PDGFRB | |
| SCHEMBL16398544 | 0.78 | PLAU (0.32) | ERBB2GRM5ALDH1A1HPGDPOLB | |
| SCHEMBL16400531 | 0.78 | ESR1 (0.42) | ALDH1A1HPGDKDM4ECYP1A2MAPK1 | |
| SCHEMBL16398655 | 0.76 | NQO2 (0.33) | ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144027-A | Cephalosporins, process for producing the same, intermediates thereof and process for producing the intermediates | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-4879381-A | ANTIBIOTICS | TOYOMA CHEMICAL COMPANY, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4673738-A | Novel intermediates of cephalosporins and process for producing 7-(substituted or unsubstituted amino)-3-substituted methyl-Δ3 -cephem-4-carboxylic acids | HANDI-PAC INC. (US) | 1987-06-16 | — | — | US | disclosed |
| US-4489072-A | BACTERICIDE, ANTIBIOTIC | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-12-18 | — | — | US | disclosed |