Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 7/20 | 0.51 |
| ▸ | NMUR1 | Q9HB89 | 7/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | GNRHR | P30968 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 10/20 | 0.47 |
| ▸ | NPY1R | P25929 | 6/20 | 0.47 |
| ▸ | NPY2R | P49146 | 5/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630914 | 0.85 | NMUR2 (0.53) | NMUR2NMUR1OPRM1NPY4RNPY1R | |
| SCHEMBL9631336 | 0.82 | NPY4R (0.51) | NMUR2NMUR1NPY4RNPY1RNPY2R | |
| SCHEMBL9631995 | 0.82 | NPY4R (0.52) | NMUR2NMUR1NPY4RNPY1RNPY2R | |
| SCHEMBL9852709 | 0.81 | NPY4R (0.52) | NMUR2NMUR1NPY4RNPY1RNPY2R | |
| SCHEMBL9852750 | 0.80 | NPY4R (0.58) | NMUR2NMUR1OPRM1NPY4RNPY1R | |
| SCHEMBL10588690 | 0.80 | NPY4R (0.61) | NMUR2NMUR1NPY4RNPY1RNPY2R | |
| SCHEMBL10586963 | 0.80 | NMUR2 (0.57) | NMUR2NMUR1DRD1GNRHROPRM1 | |
| SCHEMBL11884818 | 0.78 | NMUR2 (0.61) | NMUR2NMUR1OPRM1NPY4RNPY1R | |
| SCHEMBL11884805 | 0.78 | NMUR2 (0.61) | NMUR2NMUR1OPRM1NPY4RNPY1R | |
| SCHEMBL9629910 | 0.77 | NMUR2 (0.63) | NMUR2NMUR1NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |