Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997178 | 0.92 | GAA (0.41) | GAAHTT | |
| SCHEMBL184910 | 0.90 | GAA (0.39) | GAAHTT | |
| SCHEMBL10618484 | 0.90 | GAA (0.39) | GAAHTT | |
| SCHEMBL1333127 | 0.90 | GAA (0.39) | GAAHTT | |
| SCHEMBL818892 | 0.86 | GAA (0.44) | GAAHTT | |
| SCHEMBL7768598 | 0.82 | CYP1A2 (0.37) | GAAHTTGRIN1GRIN2B | |
| SCHEMBL28729539 | 0.81 | GAA (0.38) | GAA | |
| SCHEMBL28375219 | 0.81 | GAA (0.38) | GAA | |
| SCHEMBL996506 | 0.78 | GAA (0.48) | GAAHTT | |
| SCHEMBL30644779 | 0.75 | GAA (0.48) | GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167844-A | Stabilized against thermal and oxidative degradation | CIBA-GEIGY CORPORATION (US) | 1992-12-01 | — | — | US | disclosed |