Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.48 |
| ▸ | ADH1C | P00326 | 1/20 | 0.48 |
| ▸ | ADH1A | P07327 | 1/20 | 0.48 |
| ▸ | ADH4 | P08319 | 1/20 | 0.48 |
| ▸ | ADH7 | P40394 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385750 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| SCHEMBL11174253 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| SCHEMBL10705530 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| SCHEMBL8230983 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| SCHEMBL10613480 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| SCHEMBL8414687 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| SCHEMBL25475062 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| SCHEMBL7904756 | 1.00 | TSHR (0.68) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| Hydrochloric Acid SCHEMBL27927808 | 0.97 | TSHR (0.65) | TSHRALDH1A1ESR1S1PR2S1PR4 | |
| Hydrochloric Acid SCHEMBL28056751 | 0.97 | TSHR (0.65) | TSHRALDH1A1ESR1S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61145547-A | — | — | None | — | — | JP | disclosed |
| CN-114829433-A | Block copolymer, resin composition, stretchable conductor, electronic component, and adhesive film | 东洋油墨SC控股株式会社 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021117723-A1 | BLOCK COPOLYMER, RESIN COMPOSITION, STRETCH CONDUCTOR, ELECTRONIC DEVICE, AND PRESSURE-SENSITIVE ADHESIVE FILM | 東洋インキＳＣホールディングス株式会社 | 2021-06-17 | — | — | WO | disclosed |
| US-10421778-B2 | Isoform-selective lysine deacetylase inhibitors | WASHINGTON UNIVERSITY (US) | 2019-09-24 | — | — | US | disclosed |
| US-10005088-B2 | Flotation of sphalerite from mixed base metal sulfide ores either without or with largely reduced amount of copper sulfate addition using 2-(alkylamino)ethanethiols as collectors | LAKEHEAD UNIVERSITY (CA) | 2018-06-26 | — | — | US | disclosed |
| US-20170209873-A1 | FLOTATION OF SPHALERITE FROM MIXED BASE METAL SULFIDE ORES EITHER WITHOUT OR WITH LARGELY REDUCED AMOUNT OF COPPER SULFATE ADDITION USING 2-(ALKYLAMINO)ETHANETHIOLS AS COLLECTORS | LAKEHEAD UNIVERSEITY (CA) | 2017-07-27 | — | — | US | disclosed |
| US-5155106-A | Reduced side effects | TERUMO KABUSHIKI KAISHA (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0400144-A1 | CYSTEAMINE DERIVATIVES AND ANTI-RHEUMATIC AGENT CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-05 | — | — | EP | disclosed |
| JP-S61145547-A | SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL FOR PLATE MAKING AND ITS REDUCTION PROCESSING METHOD | KONISHIROKU PHOTO IND CO LTD | 1986-07-03 | — | — | JP | disclosed |
| EP-0164987-A2 | 7-Oxabicycloheptane substituted prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4555523-A | 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment of thrombolytic disease | E. R. SQUIBB & SONS, INC. (US) | 1985-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421778-B2 | Isoform-selective lysine deacetylase inhibitors | DOT1L, KDM1A, HDAC1 | TSHR 4222/4885ALDH1A1 529/4885ESR1 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.